Amino acid chelate (Magnesium Amino Acid Chelate, Manganese Amino Acid Chelate)absorption rate

The expression of ZnT 1, ZnT 4 and DCT1 mRNA reduces the absorption of zinc in the intestine, and thus maintains the homeostasis of zinc; the synthesis of metallothionein (metallothionein, MT) is related with the intake of dietary trace elements. Metallothionein expression was significantly enhanced in the intestinal mucosal cells of mice fasted or fed high zinc, but not significantly in the normal doses of zinc. MT-1 mRNA expression in the small intestine and liver showed that metallothionein promotes intestinal zinc absorption and retention in mucosal cells. When the intracellular free zinc concentration rises, the cellular metallothionein synthesis increases, which chelates with free zinc; In contrast, when the zinc concentration decreases, the synthesis and stabilization levels decrease, and the amount of zinc bound in metallothionein decreases. The biological efficiency of zinc binding to metallothioneins is influenced by the redox state of the cell. MT-1 mRNA expression in mouse liver and small intestine, both as Control.

Amino acid chelate (Magnesium Amino Acid Chelate, Manganese Amino Acid Chelate)absorption rate

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