酶水解法利用单一酶或者复合酶在最适条件下对大豆蛋白、虾蛋白、鲢鱼蛋白等食物蛋白质进行水解，最终制得多肽。相较于单酶水解法，复合酶水解法在制备多肽时既可以提高水解度，又能在短时间内降低酶解产物的分子量，因此当前多用复合酶水解的方法制备多肽，常用于制备亚铁螯合肽的酶有中性蛋白酶、胰蛋白酶、碱性蛋白酶等。然而，生物酶价格昂贵，为达到最佳水解结果在工艺上要严格控制反应条件，同时避免与具有复杂基质食物蛋白质的相互作用。目前关于这方面的相关研究较少，还有待进一步探索。微生物发酵法是利用微生物菌种代谢产生的蛋白酶水解底物蛋白，继而从发酵液中制备多肽产物的方法。虽然发酵法生产金属离子螯合肽仍处于起步阶段，但因其安全、经济、环保的优势受到越来越多的关注。发酵菌株具有安全性高、产酶丰富、生长迅速的优点，与酶水解法相比，微生物发酵生产多肽的成本相对较低。然而，微生物发酵法应用范围较窄，使生产多肽的发酵工业受到阻碍。因此，在工业生产中常将微生物发酵法与酶水解法相结合以提高生产效率，从而达到高效制备金属离子螯合肽的目的。

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抗坏血酸亚铁Ferrous Ascorbate、赖氨酸甘氨酸镁Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺镁Magnesium Glycinate Glutamine、柠檬酸苹果酸镁Magnesium Citrate Malate、柠檬酸锶Strontium Citrate、柠檬酸锰Manganese Citrate、柠檬酸铜Copper Citrate、天门冬氨酸锂Lithium Aspartate、抗坏血酸锰Manganese Ascorbate、牛磺酸硒Selenium Taurate。

Synthesis of polypeptide iron chelate by enzymatic hydrolysis

Enzymatic hydrolysis method uses single enzyme or complex enzyme to hydrolyze soybean protein, shrimp protein, silver carp protein and other food proteins under optimal conditions, and finally produces polypeptides. Compared with the single enzymatic hydrolysis method, the composite enzymatic hydrolysis method can not only improve the degree of hydrolysis, but also reduce the molecular weight of the enzymatic hydrolysis products in a short time. Therefore, the composite enzymatic hydrolysis method is commonly used to prepare peptides. The enzymes commonly used to prepare ferrous chelate peptides include neutral protease, trypsin, alkaline protease and so on. However, biological enzymes are expensive, and in order to achieve the best hydrolysis results, the reaction conditions must be strictly controlled in the process, while avoiding interaction with food proteins with complex substrates. At present, there are few relevant studies on this aspect, and it needs to be further explored. Microbial fermentation is a method of hydrolyzing substrate protein with protease produced by microbial strain metabolism, and then preparing polypeptide products from fermentation solution. Although the production of metal ion chelate peptides by fermentation is still in its infancy, it has attracted more and more attention because of its advantages of safety, economy and environmental protection. The fermentation strain has the advantages of high safety, abundant enzyme production and rapid growth. Compared with enzymatic hydrolysis method, the cost of microbial fermentation to produce polypeptides is relatively low. However, the application of microbial fermentation method is narrow, which hinders the fermentation industry for the production of peptides. Therefore, in industrial production, microbial fermentation and enzymatic hydrolysis are often combined to improve production efficiency, so as to achieve the purpose of efficient preparation of metal ion chelating peptides.Company's official website: www.wilincare.net welcome to buy!

Ferrous Ascorbate, Magnesium Lysinate Glycinate, Magnesium lysinate Glycinate Glutamine, Magnesium citrate malate Citrate Malate, Strontium Citrate, Manganese Citrate, Copper Citrate, Lithium Aspartate, Manganese ascorbate Ascorbate, Selenium Taurate.