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L-苏糖酸镁(Magnesium-L-threonate)对人体睡眠的影响

发表时间:2024-10-15 09:45

L-苏糖酸作为维生素C的降解产物,能够促进维生素C的吸收和利用,从而提高其活性,且与胰岛素有协同作用,作为金属离子的载体可使金属离子易与氨基酸或蛋白质结合而被动物吸收和利用,在人体中具有较高的生理活性。镁可通过抑制Na+-K+-ATP酶及镁-ATP酶,调节中枢神经递质如儿茶酚胺、阿片受体及神经DNA受体影响中枢神经功能及激素对神经功能的调节。由于脑脊液内镁离子含量高于血浆,因此单纯给予常用的镁盐如MgSO4MgCl2,对于脑内镁离子含量的提高作用甚微。L-苏糖酸镁具有很高的生物利用度,通过饮食补给L-苏糖酸镁可以显著的升高脑内的镁离子水平,通过提高脑镁可以增强大鼠的长短期记忆力,可以防止和恢复记忆缺陷,改善了学习和记忆功能;治疗精神分裂症,对突触有保护作用,可能具有治疗阿尔茨海默氏病的潜力。γ-氨基丁酸是哺乳动物中枢神经系统内最重要的氨基酸类神经递质,对神经元的活动具有抑制作用,在睡眠的调节中发挥着重要的作用,γ-氨基丁酸有促进睡眠的生理功能Mg2+可增强γ-氨基丁酸诱发的电流,通过正性变构调节机制影响 γ-氨基丁酸 A 型受体的功能。 在本实验中 L-苏糖酸镁本身无催眠作用,但与巴比妥类共同作用,一定条件下能改善睡眠

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氨基酸螯合钙Amino acid chelate calcium抗坏血酸锰Manganese Ascorbate、、赖氨酸甘氨酸镁Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺镁Magnesium Glycinate Glutamine、柠檬酸苹果酸镁Magnesium Citrate Malate、柠檬酸锶Strontium Citrate、柠檬酸锰Manganese Citrate、柠檬酸铜Copper Citrate、天门冬氨酸锂Lithium Aspartate、牛磺酸硒Selenium Taurate

Effects of Magnesium L-threonate on sleep

L-threonic acid, as a degradation product of vitamin C, can promote the absorption and utilization of vitamin C, thereby improving its activity, and has a synergistic effect with insulin. As a carrier of metal ions, metal ions can be easily combined with amino acids or proteins and be absorbed and utilized by animals, and has a high physiological activity in the human body. By inhibiting Na+-K+-ATPase and magnesium-ATPase, magnesium can regulate central neurotransmitters such as catecholamines, opioid receptors and nerve DNA receptors to affect central nervous function and hormone regulation of nerve function. Since the content of magnesium ions in cerebrospinal fluid is higher than that in plasma, the simple administration of commonly used magnesium salts such as MgSO4 or MgCl2 has little effect on the increase of magnesium ion content in brain. Magnesium L-threonate has a high bioavailability. Dietary supplementation of magnesium L-threonate can significantly increase the level of magnesium ion in the brain, enhance the short and long term memory of rats, prevent and restore memory defects, and improve learning and memory functions. Treating schizophrenia, which has a protective effect on synapses, may have potential to treat Alzheimer's disease. Gamma-aminobutyric acid (GAMma-aminobutyric acid) is the most important amino acid neurotransmitter in the central nervous system of mammals. It has inhibitory effect on the activity of neurons and plays an important role in the regulation of sleep. Gamma-aminobutyric acid has the physiological function of promoting sleep. Mg2+ can enhance the current induced by gamma-aminobutyric acid and affect the function of gamma-aminobutyric acid type A receptor through positive allosteric regulatory mechanisms. In this experiment, magnesium L-threonate itself has no hypnotic effect, but it can improve sleep under certain conditions by interacting with barbiturates.

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Amino acid chelate calcium, Manganese Ascorbate, Magnesium Lysinate Glycinate, Magnesium lysinate glycinate, magnesium glutamine Glycinate Glutamine, Magnesium Citrate Malate, Strontium Citrate, Manganese Citrate, Copper citrate Citrate, Lithium Aspartate, Selenium Taurate.


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