研究表明多肽的氨基酸组成、排列、分子量等因素，均会影响其亚铁螯合能力，其中氨基酸组成和排列是最重要的影响因素。一般来说，具有亚铁离子螯合活性的多肽大都含有半胱氨酸、组氨酸、丝氨酸、天冬氨酸和谷氨酸等氨基酸。多肽的分子量是影响螯合性能和稳定性的重要因素。越来越多的研究显示低分子量的多肽与亚铁离子具有更高的螯合能力。研究发现，一些氨基酸与亚铁离子的螯合能力是氨基酸上的特殊基团决定的。当某些氨基酸残基位于 N-末端或 C-末端时，多肽的亚铁螯合活性被 增强，位于 N-末端的组氨酸残基多肽的金属螯合能力比位于 C-末端的强。酸性氨基酸、碱性氨基酸和一些特殊氨基酸对亚铁离子有很强的螯合能力。例如，组氨酸和谷氨酸分别以咪唑环、 γ-COO-提供了更多的铁结合位点，从而具有较好的螯合能力。

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抗坏血酸亚铁Ferrous Ascorbate、赖氨酸甘氨酸镁Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺镁Magnesium Glycinate Glutamine、柠檬酸苹果酸镁Magnesium Citrate Malate、柠檬酸锶Strontium Citrate、柠檬酸锰Manganese Citrate、柠檬酸铜Copper Citrate、天门冬氨酸锂Lithium Aspartate、抗坏血酸锰Manganese Ascorbate、牛磺酸硒Selenium Taurate。

The key factors influencing the chelating ability of polypeptides to ferrous

Studies have shown that the amino acid composition, arrangement and molecular weight of polypeptides can affect their ferrous chelating ability, among which the amino acid composition and arrangement are the most important factors. In general, polypeptides with ferrous ion chelating activity mostly contain amino acids such as cysteine, histidine, serine, aspartate and glutamic acid. The molecular weight of peptides is an important factor affecting the chelation performance and stability. More and more studies have shown that low molecular weight polypeptides have higher chelation ability with ferrous ions. It has been found that the chelating ability of some amino acids with ferrous ions is determined by special groups on amino acids. When some amino acid residues are located at the N-terminal or C-terminal, the ferrous chelating activity of the polypeptide is enhanced, and the metal chelating ability of the histidine residues in the n-terminal is stronger than that in the C-terminal. Acidic amino acids, basic amino acids and some special amino acids have strong chelating ability to ferrous ions. For example, histidine and glutamate provide more iron-binding sites in imidazole ring and gamma-COO -, respectively, and thus have better chelating ability.

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Ferrous Ascorbate, Magnesium Lysinate Glycinate, Magnesium lysinate Glycinate Glutamine, Magnesium citrate malate Citrate Malate, Strontium Citrate, Manganese Citrate, Copper Citrate, Lithium Aspartate, Manganese ascorbate Ascorbate, Selenium Taurate.